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1

Crystal structures of pheasant and guinea fowl egg-white lysozymes

Julien Lescar, Hélene Souchon, Pedro M. Alzari

Journal:

Protein Science

Year:

1994

Language:

english

File:

PDF, 6.91 MB

english, 1994

2

L'organisation de la formation professionnelle et de l'éducation permanente en France

Review by: Léon LESCAR

Journal:

Revue française de pédagogie

Year:

1973

Language:

french

File:

PDF, 257 KB

french, 1973

3

Structure of the human metapneumovirus polymerase phosphoprotein complex

Pan, Junhua, Qian, Xinlei, Lattmann, Simon, El Sahili, Abbas, Yeo, Tiong Han, Jia, Huan, Cressey, Tessa, Ludeke, Barbara, Noton, Sarah, Kalocsay, Marian, Fearns, Rachel, Lescar, Julien

Journal:

Year:

2019

File:

PDF, 13.79 MB

2019

4

Conventional and unconventional mechanisms for capping viral mRNA

Decroly, Etienne, Ferron, François, Lescar, Julien, Canard, Bruno

Journal:

Nature Reviews Microbiology

Year:

2011

Language:

english

File:

PDF, 1.23 MB

english, 2011

5

Polymerases of hepatitis C viruses and flaviviruses: Structural and mechanistic insights and drug development

Caillet-Saguy, Célia, Lim, Siew Pheng, Shi, Pei-Yong, Lescar, Julien, Bressanelli, Stéphane

Journal:

Antiviral Research

Year:

2014

Language:

english

File:

PDF, 2.44 MB

english, 2014

6

“Brett character” in wine: Is there a consensus among professional assessors? A perceptual and conceptual approach

Tempère, S., Cuzange, E., Schaaper, M.H., de Lescar, R., de Revel, G., Sicard, G.

Journal:

Food Quality and Preference

Year:

2014

Language:

english

File:

PDF, 855 KB

english, 2014

7

The flavivirus NS2B–NS3 protease–helicase as a target for antiviral drug development

Luo, Dahai, Vasudevan, Subhash G., Lescar, Julien

Journal:

Antiviral Research

Year:

2015

Language:

english

File:

PDF, 2.34 MB

english, 2015

8

Engineering a Catalytically Efficient Recombinant Protein Ligase

Yang, Renliang, Wong, Yee Hwa, Nguyen, Giang K T, Tam, James P, Lescar, Julien, Wu, Bin

Journal:

Journal of the American Chemical Society

Year:

2017

Language:

english

File:

PDF, 1.19 MB

english, 2017

9

Structure of the human metapneumovirus polymerase phosphoprotein complex

Pan, Junhua, Qian, Xinlei, Lattmann, Simon, El Sahili, Abbas, Yeo, Tiong Han, Jia, Huan, Cressey, Tessa, Ludeke, Barbara, Noton, Sarah, Kalocsay, Marian, Fearns, Rachel, Lescar, Julien

Journal:

Year:

2019

Language:

english

File:

PDF, 13.79 MB

english, 2019

10

Inhibition of HIV protease by monoclonal antibodies

P. Rezacova, J. Brynda, M. Fabry, M. Horejsi, R. Stouracova, J. Lescar, V. Chitarra, M. M. Riottot, J. Sedlacek, G. A. Bentley

Journal:

Journal of Molecular Recognition

Year:

2002

Language:

english

File:

PDF, 272 KB

english, 2002

11

NMR and crystallographic structures of the FK506 binding domain of human malarial parasite Plasmodium vivax FKBP35

Reema Alag, Insaf A. Qureshi, Nagakumar Bharatham, Joon Shin, Julien Lescar, Ho Sup Yoon

Journal:

Protein Science

Year:

2010

Language:

english

File:

PDF, 717 KB

english, 2010

12

Preliminary crystallographic studies of an anti-HIV-1 protease antibody that inhibits enzyme activity

Julien Lescar, Renata Stouracova, Marie-Madeleine Riottot, Véronique Chitarra, Jiri Brynda, Milan Fabry, Magda Horejsi, Juraj Sedlacek, Graham A. Bentley

Journal:

Protein Science

Year:

1996

Language:

english

File:

PDF, 300 KB

english, 1996

13

Crystallization, preliminary X-ray diffraction study, and crystal packing of a complex between anti-Hen lysozyme antibody F9.13.7 and Guinea-fowl lysozyme

Julien Lescar, Marie-Madeleine Riottot, Hélène Souchon, Véronique Chitarra, Graham A. Bentley, Jorge Navaza, Pedro M. Alzari, Roberto J. Poljak

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1993

Language:

english

File:

PDF, 360 KB

english, 1993

14

Structure of a flavivirus envelope glycoprotein in its low-pH-induced membrane fusion conformation

Bressanelli, Stéphane, Stiasny, Karin, Allison, Steven L, Stura, Enrico A, Duquerroy, Stéphane, Lescar, Julien, Heinz, Franz X, Rey, Félix A

Journal:

The EMBO Journal

Year:

2004

Language:

english

File:

PDF, 718 KB

english, 2004

15

Inhibition of the HIV-1 and HIV-2 proteases by a monoclonal antibody

Julien Lescar, Jiri Brynda, Graham A. Bentley, Marie-Madeleine Riottot, Véronique Chitarra, Pavlina Rezacova, Renata Stouracova, Milan Fabry, Magda Horejsi, Juraj Sedlacek

Journal:

Protein Science

Year:

1999

Language:

english

File:

PDF, 78 KB

english, 1999

16

The flavivirus polymerase as a target for drug discovery

Hélène Malet, Nicolas Massé, Barbara Selisko, Jean-Louis Romette, Karine Alvarez, Jean Claude Guillemot, Hughes Tolou, Thai Leong Yap, Subash G. Vasudevan, Julien Lescar, Bruno Canard

Journal:

Antiviral Research

Year:

2008

Language:

english

File:

PDF, 1.78 MB

english, 2008

17

A scintillation proximity assay for dengue virus NS5 2′-O-methyltransferase—kinetic and inhibition analyses

Siew Pheng Lim, Daying Wen, Thai Leong Yap, Chung Ka Yan, Julien Lescar, Subhash G. Vasudevan

Journal:

Antiviral Research

Year:

2008

Language:

english

File:

PDF, 714 KB

english, 2008

18

Towards the design of antiviral inhibitors against flaviviruses: The case for the multifunctional NS3 protein from Dengue virus as a target

Julien Lescar, Dahai Luo, Ting Xu, Aruna Sampath, Siew Pheng Lim, Bruno Canard, Subhash G. Vasudevan

Journal:

Antiviral Research

Year:

2008

Language:

english

File:

PDF, 967 KB

english, 2008

19

RNA-dependent RNA polymerases from flaviviruses and Picornaviridae

Julien Lescar, Bruno Canard

Journal:

Current Opinion in Structural Biology

Year:

2009

Language:

english

File:

PDF, 479 KB

english, 2009

20

The Nucleocapsid Protein of Coronavirus Infectious Bronchitis Virus: Crystal Structure of Its N-Terminal Domain and Multimerization Properties

Hui Fan, Amy Ooi, Yong Wah Tan, Sifang Wang, Shouguo Fang, Ding Xiang Liu, Julien Lescar

Journal:

Year:

2005

Language:

english

File:

PDF, 612 KB

english, 2005

21

Structure and Interactions at the Viral Surface of the Envelope Protein E1 of Semliki Forest Virus

Alain Roussel, Julien Lescar, Marie-Christine Vaney, Gisela Wengler, Gerd Wengler, Félix A. Rey

Journal:

Year:

2006

Language:

english

File:

PDF, 1.08 MB

english, 2006

22

Higher catalytic efficiency of N-7-methylation is responsible for processive N-7 and 2′-O methyltransferase activity in dengue virus

Ka Yan Chung, Hongping Dong, Alexander Theodore Chao, Pei-Yong Shi, Julien Lescar, Siew Pheng Lim

Journal:

Year:

2010

Language:

english

File:

PDF, 817 KB

english, 2010

23

Biochemical and genetic characterization of dengue virus methyltransferase

Hongping Dong, David C. Chang, Xuping Xie, Ying Xiu Toh, Ka Yan Chung, Gang Zou, Julien Lescar, Siew Pheng Lim, Pei-Yong Shi

Journal:

Year:

2010

Language:

english

File:

PDF, 2.29 MB

english, 2010

24

Cat and mouse: viral cyclins and CDKs

Journal:

Trends in Biochemical Sciences

Year:

2002

Language:

english

File:

PDF, 14 KB

english, 2002

25

Structural Basis of HIV-1 and HIV-2 Protease Inhibition by a Monoclonal Antibody

Pavlina Rezacova, Julien Lescar, Jiri Brynda, Milan Fabry, Magda Horejsi, Juraj Sedlacek, Graham A. Bentley

Journal:

Year:

2001

Language:

english

File:

PDF, 659 KB

english, 2001

26

Effect of Fungicide Application on Cereals in France

Journal:

Year:

1981

Language:

english

File:

PDF, 521 KB

english, 1981

27

Crystallographic structure of ubiquitin in complex with cadmium ions

Insaf A Qureshi, Francois Ferron, Cheah Chen Seh, Peter Cheung, Julien Lescar

Journal:

BMC Research Notes

Year:

2009

Language:

english

File:

PDF, 813 KB

english, 2009

28

Three-dimensional structure of an fab-peptide complex: structural basis of HIV-1 protease inhibition by a monoclonal antibody

Julien Lescar, Renata Stouracova, Marie-Madeleine Riottot, Véronique Chitarra, Jiri Brynda, Milan Fabry, Magda Horejsi, Juraj Sedlacek, Graham A Bentley

Journal:

Journal of Molecular Biology

Year:

1997

Language:

english

File:

PDF, 744 KB

english, 1997

29

Expression of SARS-coronavirus envelope protein in Escherichia coli cells alters membrane permeability

Y. Liao, J. Lescar, J.P. Tam, D.X. Liu

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 580 KB

english, 2004

30

Induced-fit upon Ligand Binding Revealed by Crystal Structures of the Hot-dog Fold Thioesterase in Dynemicin Biosynthesis

Chong Wai Liew, Andrew Sharff, Masayo Kotaka, Rong Kong, Huihua Sun, Insaf Qureshi, Gérard Bricogne, Zhao-Xun Liang, Julien Lescar

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 2.71 MB

english, 2010

31

Crystal structure of a cross-reaction complex between an anti-HIV-1 protease antibody and an HIV-2 protease peptide

Pavlina Rezacova, Jiri Brynda, Julien Lescar, Milan Fabry, Magda Horejsi, Irena Sieglova, Juraj Sedlacek, Graham A. Bentley

Journal:

Journal of Structural Biology

Year:

2005

Language:

english

File:

PDF, 756 KB

english, 2005

32

The Fusion Glycoprotein Shell of Semliki Forest Virus: An Icosahedral Assembly Primed for Fusogenic Activation at Endosomal pH

Julien Lescar, Alain Roussel, Michelle W. Wien, Jorge Navaza, Stephen D. Fuller, Gisela Wengler, Gerd Wengler, Félix A. Rey

Journal:

Year:

2001

Language:

english

File:

PDF, 2.58 MB

english, 2001

33

Rigidifying Acyl Carrier Protein Domain in Iterative Type I PKS CalE8 Does Not Affect Its Function

Lim, Jackwee, Sun, Huihua, Fan, Jing-Song, Hameed, Iman Fahim, Lescar, Julien, Liang, Zhao-Xun, Yang, Daiwen

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 713 KB

english, 2012

34

Crystal Structure of the FK506 Binding Domain of Plasmodium falciparum FKBP35 in Complex with FK506 †‡

Kotaka, Masayo, Ye, Hong, Alag, Reema, Hu, Guangan, Bozdech, Zbynek, Preiser, Peter Rainer, Yoon, Ho Sup, Lescar, Julien

Journal:

Year:

2008

Language:

english

File:

PDF, 851 KB

english, 2008

35

Ten years of dengue drug discovery: Progress and prospects

Lim, Siew Pheng, Wang, Qing-Yin, Noble, Christian G., Chen, Yen-Liang, Dong, Hongping, Zou, Bin, Yokokawa, Fumiaki, Nilar, Shahul, Smith, Paul, Beer, David, Lescar, Julien, Shi, Pei-Yong

Journal:

Antiviral Research

Year:

2013

Language:

english

File:

PDF, 1.38 MB

english, 2013

36

A Crystal Structure of the Dengue Virus Non-structural Protein 5 (NS5) Polymerase Delineates Interdomain Amino Acid Residues That Enhance Its Thermostability and de Novo Initiation Activities

Lim, S. P., Koh, J. H. K., Seh, C. C., Liew, C. W., Davidson, A. D., Chua, L. S., Chandrasekaran, R., Cornvik, T. C., Shi, P.-Y., Lescar, J.

Journal:

Journal of Biological Chemistry

Year:

2013

Language:

english

File:

PDF, 3.48 MB

english, 2013

37

Dimerization of Flavivirus NS4B Protein

Zou, J., Xie, X., Lee, L. T., Chandrasekaran, R., Reynaud, A., Yap, L., Wang, Q.-Y., Dong, H., Kang, C., Yuan, Z., Lescar, J., Shi, P.-Y.

Journal:

Journal of Virology

Year:

2014

Language:

english

File:

PDF, 1.69 MB

english, 2014

38

Products of the iterative polyketide synthases in 9- and 10-membered enediyne biosynthesis

Sun, Huihua, Kong, Rong, Zhu, Di, Lu, Min, Ji, Qiang, Liew, Chong Wai, Lescar, Julien, Zhong, Guofu, Liang, Zhao-Xun

Journal:

Chemical Communications

Year:

2009

Language:

english

File:

PDF, 1.03 MB

english, 2009

39

Generation and characterization of mouse monoclonal antibodies against NS4B protein of dengue virus

Xie, Xuping, Zou, Jing, Wang, Qing-Yin, Noble, Christian G., Lescar, Julien, Shi, Pei-Yong

Journal:

Year:

2014

Language:

english

File:

PDF, 4.38 MB

english, 2014

40

Assessment of Dengue virus helicase and methyltransferase as targets for fragment-based drug discovery

Coutard, Bruno, Decroly, Etienne, Li, Changqing, Sharff, Andrew, Lescar, Julien, Bricogne, Gérard, Barral, Karine

Journal:

Antiviral Research

Year:

2014

Language:

english

File:

PDF, 1.60 MB

english, 2014

41

Lyso-myristoyl phosphatidylcholine micelles sustain the activity of Dengue non-structural (NS) protein 3 protease domain fused with the full-length NS2B

Huang, Qiwei, Li, Qingxin, Joy, Joma, Chen, Angela Shuyi, Ruiz-Carrillo, David, Hill, Jeffrey, Lescar, Julien, Kang, Congbao

Journal:

Protein Expression and Purification

Year:

2013

Language:

english

File:

PDF, 1.37 MB

english, 2013

42

Biomimetic Production of Silk-Like Recombinant Squid Sucker Ring Teeth Proteins

Ding, Dawei, Guerette, Paul A., Hoon, Shawn, Kong, Kiat Whye, Cornvik, Tobias, Nilsson, Martina, Kumar, Akshita, Lescar, Julien, Miserez, Ali

Journal:

Biomacromolecules

Year:

2014

Language:

english

File:

PDF, 5.79 MB

english, 2014

43

Aspergillus fumigatus harbouring the sole Y121F mutation shows decreased susceptibility to voriconazole but maintained susceptibility to itraconazole and posaconazole

Lescar, J., Meyer, I., Akshita, K., Srinivasaraghavan, K., Verma, C., Palous, M., Mazier, D., Datry, A., Fekkar, A.

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2014

Language:

english

File:

PDF, 344 KB

english, 2014

44

Structure of the Functional Form of the Mosquito Larvicidal Cry4Aa Toxin from Bacillus thuringiensis at a 2.8-Angstrom Resolution

Boonserm, P., Mo, M., Angsuthanasombat, C., Lescar, J.

Journal:

Journal of Bacteriology

Year:

2006

Language:

english

File:

PDF, 1.21 MB

english, 2006

45

Crystal Structure of the Dengue Virus RNA-Dependent RNA Polymerase Catalytic Domain at 1.85-Angstrom Resolution

Yap, T. L., Xu, T., Chen, Y.-L., Malet, H., Egloff, M.-P., Canard, B., Vasudevan, S. G., Lescar, J.

Journal:

Journal of Virology

Year:

2007

Language:

english

File:

PDF, 2.23 MB

english, 2007

46

Bioorthogonal Cleavage and Exchange of Major Histocompatibility Complex Ligands by Employing Azobenzene-Containing Peptides

Choo, Joanna A. L., Thong, Sock Yue, Yap, Jiawei, van Esch, Wim J. E., Raida, Manfred, Meijers, Rob, Lescar, Julien, Verhelst, Steven H. L., Grotenbreg, Gijsbert M.

Journal:

Angewandte Chemie International Edition

Year:

2014

Language:

english

File:

PDF, 1.55 MB

english, 2014

47

Discovery and characterization of pseudocyclic cystine-knot α-amylase inhibitors with high resistance to heat and proteolytic degradation

Nguyen, Phuong Q. T., Wang, Shujing, Kumar, Akshita, Yap, Li J., Luu, Thuy T., Lescar, Julien, Tam, James P.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.43 MB

english, 2014

48

The C-terminal 50 Amino Acid Residues of Dengue NS3 Protein Are Important for NS3-NS5 Interaction and Viral Replication

Tay, Moon Y. F., Saw, Wuan Geok, Zhao, Yongqian, Chan, Kitti W. K., Singh, Daljit, Chong, Yuwen, Forwood, Jade K., Ooi, Eng Eong, Grüber, Gerhard, Lescar, Julien, Luo, Dahai, Vasudevan, Subhash G.

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 4.46 MB

english, 2015

49

Mapping the Interactions between the NS4B and NS3 Proteins of Dengue Virus

Zou, Jing, Lee, Le Tian, Wang, Qing Yin, Xie, Xuping, Lu, Siyan, Yau, Yin Hoe, Yuan, Zhiming, Geifman Shochat, Susana, Kang, Congbao, Lescar, Julien, Shi, Pei-Yong, Dermody, T. S.

Journal:

Journal of Virology

Year:

2015

Language:

english

File:

PDF, 3.53 MB

english, 2015

50

A Structural Hypothesis for the Transition between Bent and Extended Conformations of the Leukocyte beta2 Integrins

Shi, M., Foo, S. Y., Tan, S.-M., Mitchell, E. P., Law, S. K. A., Lescar, J.

Journal:

Journal of Biological Chemistry

Year:

2007

Language:

english

File:

PDF, 937 KB

english, 2007

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